[IMG] Chemokines and their receptors play a central role in the pathogenesis of numerous, perhaps all, acute and chronic inflammatory diseases....
[IMG] There is an urgent need to develop new approaches to treat conditions as- ciated with the aging global population. The surgeon’s approach to...
[IMG] A collection of cutting-edge methods for investigating G protein signaling from a variety of perspectives ranging from in vitro biochemistry...
[IMG] Functional genomics is a young discipline whose origin can be traced back to the late 1980s and early 1990s, when molecular tools became...
[IMG] A comprehensive collection of readily reproducible techniques for the manipulation of recombinant plasmids using the bacterial host E. coli....
[IMG] Since the discovery of p53 as a tumor suppressor, numerous methods have evolved to reveal the unique structural features and biochemical...
[IMG] Since the discovery that protein kinase C (PKC) transduces the ab- dance of signals that result in phospholipid hydrolysis, this enzyme has...
[IMG] For decades it has been known that structured conformations are important for the proper functioning of most cellular proteins. However,...
[IMG] Biological systems are very special substrates for engineering―uniquely the products of evolution, they are easily redesigned by similar...
[IMG] Directed evolution comprises two distinct steps that are typically applied in an iterative fashion: (1) generating molecular diversity and...
[IMG] Maurizio Federico has assembled a panel of outstanding experimenters to detail all the theoretical and practical aspects of lentivirus...
[IMG] Knowledge of the three-dimensional structure of a protein is absolutely required for the complete understanding of its function. The spatial...
[IMG] Studies of membrane transporters have had great impact on our und- standing human diseases and the design of effective drugs. About 30% of...
[IMG] Drawing on the highly successful first edition, this newly-revised second edition covers the many advances made in PCR technology since the...
[IMG] Inflammation has been described as the basis of many pathologies of human disease. When one considers the updated signs of inflammation,...
[IMG] This collection of robust, readily reproducible methods for microarray-based studies includes expert guidance in the optimal data analysis...
[IMG] It has become clear that tumors result from excessive cell proliferation and a corresponding reduction in cell death caused by the...
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