Methods in Enzymology Vol.78 Interferons, Part A

Discussion in 'Methods in Enzymology Book Series' started by admin, Jul 19, 2016.

  1. admin

    admin Thư Viện Sách Việt Staff Member Quản Trị Viên

    Interferon (IF), the body's most rapidly produced defense against viruses, is a protein secreted by body cells when they are stimulated by viruses, bacteria, foreign cells, foreign macromolecules, or numerous other compounds. The secreted interferon then stimulates surrounding cells to produce other proteins, which, in turn, may regulate virus multiplication, the immune response, cell growth, and other cell functions. There are three distinct types of interferon––leukocyte interferon, fibroblast interferon, and immune interferon––depending on the type of stimulus and the type of cell stimulated. These are coded by different structural genes as determined by distinct amino acid sequences and distinct antigenicities. The binding of interferon to a cellular surface receptor initiates the induction of some intracellular proteins. The variety of functional cellular effects of interferon suggests a corresponding variety of biochemical effects. For production of a particular type of interferon, it is necessary to select an appropriate producer cell and an appropriate stimulus. Moreover, medical studies indicate that interferon is promising as a treatment for virus infections and, perhaps, cancer and autoimmune diseases, so that great interest in the interferons is generated.
    • Series: Methods in Enzymology (Book 78)
    • Hardcover: 680 pages
    • Publisher: Academic Press; 1 edition (January 11, 1982)
    • Language: English
    • ISBN-10: 0121819787
    • ISBN-13: 978-0121819781
    • Product Dimensions: 6 x 9 inches
    Link Download
    Last edited: Nov 15, 2021

Share This Page