Driving further the research on mammalian alkaline phosphatase structure and function, Phosphatase Modulators collects expert contributions into one “how to” manual for basic scientists interested in initiating a drug discovery effort. While this book contains the traditional method chapters and some typical reviews on the structure and known functions of phosphatases, other contributions are meant to discuss approaches and alternatives useful in making “go/no-go” decisions in high throughput screening (HTS) and lead optimization campaigns. Many chapters focus on tissue-nonspecific alkaline phosphatase (TNAP) as well as protein phosphatases. Written for the highly successful Methods in Molecular Biology series, chapters in this volume include the kind of detail and key implementation advice that promotes reproducible results. Series: Methods in Molecular Biology (Book 1053) Hardcover: 315 pages Publisher: Humana Press; 2013 edition (July 17, 2013) Language: English ISBN-10: 1627035613 ISBN-13: 978-1627035613 Product Dimensions: 7.2 x 0.9 x 10.3 inches Link Download http://nitroflare.com/view/B48A625F49A37C6https://drive.google.com/drive/folders/1yLBzZ1rSQoNjmWeJTZ3WGQHg04L1
