Methods in Molecular Biology Vol.1320 Nucleic Acid Crystallography Methods and Protocols

This volume includes comprehensive and up-to-date coverage of all nucleic acid-specific steps used in X-ray crystallography, from macromolecule production to structure determination. Chapters dedicated to RNA preparation and crystallogenesis will be of interest to beginners, while chapters focused on data collection, phasing and refinement will be particularly useful to researchers with a higher level of expertise. Several functional case studies are also presented in the last part of the book. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

• Series: Methods in Molecular Biology (Book 1320)
• Hardcover: 356 pages
• Publisher: Humana Press; 1st ed. 2015 edition (July 31, 2015)
• Language: English
• ISBN-10: 1493927620
• ISBN-13: 978-1493927623
• Product Dimensions: 10.4 x 7.2 x 1 inches

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