Pui-Yan Kwok, MD, PhD, has assembled a comprehensive collection of readily reproducible techniques for the difficult process of single nucleotide polymorphisms (SNP) discovery and genotyping. These cutting-edge protocols for mutation/SNP detection utilize denaturing high-performance liquid chromatography (dHPLC), single-strand conformation polymorphism (SSCP), conformation-sensitive gel electrophoresis (CSGE), chemical cleavage, and direct sequencing. Equally powerful and up-to-date methods are given for genotyping SNPs, including molecular beacons, the Taqman assay, single-base extension approaches, pyrosequencing, ligation, the Invader assay, and primer extension with mass spectrometry detection. Series: Methods in Molecular Biology (Book 212) Hardcover: 288 pages Publisher: Humana Press; 1 edition (October 7, 2002) Language: English ISBN-10: 0896039684 ISBN-13: 978-0896039681 Product Dimensions: 0.8 x 6.2 x 9 inches Link Download http://nitroflare.com/view/2021F6D988262D0https://drive.google.com/drive/folders/1yLBzZ1rSQoNjmWeJTZ3WGQHg04L1
