Methods in Molecular Biology Vol.281 Checkpoint Controls and Cancer 2-Activation and Regulation

Volume 2: Activation and Regulation Protocols, Axel H. Schönthal, PhD, marshals a prestigious panel of researchers working at the cutting edges of their fields to present readily reproducible experimental protocols for the study of the molecular components of checkpoint controls and their regulation. Described in step-by-step detail, these powerful techniques offer such novel approaches as the use of genome databases and siRNA to analyze how cells of the human body can escape proper surveillance to grow into a tumor. Additional experimental methods are provided for the manipulation of checkpoint pathways and the analysis of the resulting consequences for the cellular phenotype. The earlier first volume, Reviews and Model Systems, comprehensively describes the complexities of checkpoint controls and the model systems available to study them.

• Series: Methods in Molecular Biology
  
• Hardcover: 358 pages
• Publisher: Humana Press; 2004 edition (June 24, 2004)
• Language: English
• ISBN-10: 1588295001
• ISBN-13: 978-1588295002
• Product Dimensions: 6.1 x 0.9 x 9.2 inches

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