Methods in Molecular Biology Vol.468 Wnt Signaling Volume 1-Pathway Methods and Mammalian Models

Since their discovery, Wnt signaling molecules have been shown to control key events in embryogenesis, to maintain tissue homeostasis in the adult and, when aberrantly activated, to promote human degenerative diseases and cancer, thus making them a vital area of study. Wnt Signaling: Methods and Protocols examines both biochemical assays and vertebrate and invertebrate model systems to provide a point of reference to current molecular protocols and the diverse model systems employed to study this important signaling pathway. In Volume 1, Pathway Methods and Mammalian Models, assays to measure activation of the diverse Wnt signaling pathways are explored, along with a selection of models and strategies used to study mammalian Wnt/FZD fuction, from protein-protein interaction and simple cell line models to organoid cultures and mouse models. As a volume in the highly successful Methods in Molecular Biology™ series, chapters contain readily reproducible laboratory protocols, complete with lists of necessary equipment and reagents and the Notes section, which reveals helpful troubleshooting tips.

• Series: Methods in Molecular Biology (Book 468)
• Hardcover: 336 pages
• Publisher: Humana Press; 2008 edition
• Language: English
• ISBN-10: 1588299120
• ISBN-13: 978-1588299123
• Product Dimensions: 1 x 7.8 x 10.2 inches

Link Download
http://nitroflare.com/view/7190223E3C48BA2
https://drive.google.com/drive/folders/1yLBzZ1rSQoNjmWeJTZ3WGQHg04L1