Methods in Molecular Biology Vol.556 Microarray Analysis of the Physical Genome Methods and Protocol

In the early years of microarray technology, efforts were directed mainly at profiling expressed genes, while recently the microarray platform has been adapted into diverse applications directed toward the investigation of the physical genome. In Microarray Analysis of the Physical Genome: Methods and Protocols, experts in the field cover DNA microarray applications for the detection and characterization of genomic DNA-associated copy number alteration, loss of heterozygosity (LOH), cytosine methylation, protein binding sites, regulatory elements, and replication timing, with an emphasis on higher eukaryote (animal) and cancer genomes. Written in the highly successful Methods in Molecular Biology™ series format, chapters include a brief introduction to their respective subjects, lists of the necessary materials and reagents, step-by-step protocols, and time-saving notes on troubleshooting and avoiding known pitfalls.

• Series: Methods in Molecular Biology (Book 556)
• Paperback: 224 pages
• Publisher: Humana Press; 2009 edition (December 6, 2011)
• Language: English
• ISBN-10: 1617794902
• ISBN-13: 978-1617794902
• Product Dimensions: 7.6 x 0.5 x 10.2 inches

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