Methods in Molecular Biology Vol.988 Glycosylation Engineering of Biopharmaceuticals

Glyco-engineering is being developed as a method to control the composition of carbohydrates and to enhance the pharmacological properties of monoclonal antibodies (mAbs) and other proteins. In Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols, experts in the field provide readers with production and characterization protocols of glycoproteins and glyco-engineered biopharmaceuticals with a focus on mAbs. The volume is divided in four complementary parts dealing with glyco-engineering of therapeutic proteins, glycoanalytics, glycoprotein complexes characterization, and PK/PD assays for therapeutic antibodies. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

• Series: Methods in Molecular Biology (Book 988)
• Hardcover: 355 pages
• Publisher: Humana Press; 2013 edition (March 9, 2013)
• Language: English
• ISBN-10: 1627033262
• ISBN-13: 978-1627033268
• Product Dimensions: 7.2 x 1 x 10.3 inches

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